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| Today’s Top Story
Study Finds Preoperative Cefazolin Dose in TJA Patients with Penicillin Allergies Is Safe and Effective
A retrospective study of 2,451 total joint arthroplasties (TJAs) assessed the clinical viability of giving patients with a penicillin allergy (PA) perioperative cefazolin under anesthesia. The study was published in the Jan. 15 issue of the Journal of the AAOS®. The primary outcomes included allergic reactions and postoperative infection. Cefazolin was administered to 87.1 percent of patients, including 143 PA patients. There were no statistical differences noted between patients with and without PA regarding allergic reactions. Patients who received cefazolin had a lower rate of periprosthetic joint infection compared with those receiving other antibiotics (2.9 percent versus 5.5 percent).
Read the abstract… |
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| In Other News
Prospective Study: Charting Neuropathic Pain, Anxiety, Depression, and Pain Catastrophizing after TKR
Orthopaedics & Traumatology: Surgery & Research published a prospective study evaluating neuropathic pain, anxiety and depressive symptoms, and pain catastrophizing following total knee replacement (TKR) for primary osteoarthritis. A total of 129 patients comprised the study population; patient demographics and patient responses to seven questionnaires evaluating the primary outcomes were collected pre- and postoperatively (six months and at a mean of 7.5 years) Comparing data pre- and six months postsurgery, knee pain, anxiety, and catastrophizing improved; however, depressive symptoms remained unchanged. Neuropathic pain was observed in 30 percent and 18 percent after six months and 7.5 years, respectively.
Read the abstract… |
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| Study Investigates Incidence of and Risk Factors Associated with Delayed Wound Closure in ORIF Patients
One of five ORIF (open reduction–internal fixation) patients with both-bone forearm fractures underwent delayed wound closure, according to a retrospective study in Clinical Orthopaedics and Related Research. The primary outcome was the utilization of delayed wound closure, and univariate logistic regression was utilized to identify risk factors associated with delayed wound closure. Of the 65 patients included in the study, 20 percent underwent delayed wound closure. Eighteen percent of delayed closures occurred in patients who had high-energy injuries, and 14 precent occurred in patients who had open fractures. Male sex was found to be independently associated with delayed wound closure.
Read the abstract… |
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| Meta-analysis: PRP Injections Are Not Superior to Placebos to Treat Tendinopathy
In a meta-analysis published in the Clinical Journal of Sports Medicine, platelet-rich plasma (PRP) injections were not superior to placebos for the treatment of tendinopathy. The outcomes of 13 randomized controlled trials evaluating the clinical efficacy of PRP versus placebo for the treatment of tendinopathy were evaluated using random-effects models. After a pooled-analysis, no significant differences regarding pain relief were observed at four to six weeks, 12 weeks, and >24 weeks. Additionally, there were no significant differences in relief or functional improvement for different types of tendinopathies, treatment regimens, leukocyte concentrations, or cointerventions.
Read the abstract… |
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| Prospective Case Series Assesses Long-term Outcomes following Arthroscopic Lift-drill-fill-fix of Primary Osteochondral Lesions of the Talus
Eighteen patients undergoing fixation for a chronic primary osteochondral lesion of the talus using the Lift-drill-fill-fix technique had a procedure survival rate of 87 percent after a mean seven-year follow-up, per a prospective study in Knee Surgery, Sports Traumatology, Arthroscopy. The Numeric Rating Scale (NRS) of pain, change in Foot and Ankle Outcome Scores (FAOS), and procedure survival were measured pre- and postoperatively. NRS scores during walking significantly improved preoperatively and at final follow-up (7 versus 0), and NRS during running improved from 8 to 2. The median FAOS significantly improved on all subscales, excluding the symptoms subscale.
Read the study… |
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| AAOS Now
Newly Revised CPG Offers Guidance on Managing ACL Injuries
The AAOS Board of Directors approved a substantial update to the Clinical Practice Guideline (CPG) for the Management of Anterior Cruciate Ligament (ACL) Injuries, which was first issued in 2014. The 2022 version updated 12 of the 24 evidence-based recommendations offered in the 2014 edition. Noteworthy additions include two new recommendations: a strong recommendation favoring ACL reconstruction (ACLR) over repair and a moderate-strength recommendation stating that anterolateral ligament/lateral extra-articular tenodesis merits consideration in select patients undergoing ACLR with hamstring autograft.
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| Your AAOS
Virtual Course: AAOS and OTA Present Daily Dilemmas in Trauma
On Saturday, April 1, this single-day virtual course presented by AAOS and the Orthopaedic Trauma Association (OTA) will provide the latest updates in orthopaedic trauma. Led by Paul Tornetta III, MD, FAAOS, and J. Tracy Watson, MD, FAAOS, along with more than 25 renowned faculty, this case-based course delivers insights on fracture fixation—both operative and nonoperative—as well as complication management, outcomes, and more. The interactive live course is comprised primarily of small-group case reviews. This virtual package also includes more than 40 prerecorded lectures and access to all content for 60 days.
Register now… |
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